Self-taught, but initiated to painting by his father, he devoted himself to this art since 1919. Then he studied esotericism and oriental philosophies. In 1925, Le Corbusier drew up the plans for a house for the artist, the Maison Guiette, built in Antwerp. This house-studio is Le Corbusier's only building in Belgium. Initially known for his cubist works before the Second World War, René Guiette became a member of the Compagnie de l'art brut created by Jean Dubuffet from 1949 onwards. He will end his creative career in a materialist abstraction that he will not abandon until his death in 1976.